PUBLICATIONS

Pioneering Research
Division

2022

  1. Hashimoto S, Matsuba Y, Takahashi M, Kamano N, Watamura N, Sasaguri H, Takado Y, Yoshihara Y, Saito T, Saido TC: Neuronal glutathione loss leads to neurodegeneration involving gasdermin activation. Sci Rep 13: 1109, 2023.

International Joint
Research Division

2022

  1. Tsubaki H, Mendsaikhan A, Buyandelger U, Tooyama I, Walker DG. Localization of thioredoxin-interacting protein in aging and Alzheimer’s disease brains. NeuroSci. 3:166-185, 2022.
  2. Takata K, Kimura H, Yanagisawa D, Harada K, Nishimura K, Kitamura Y, Shimohama S, Tooyama I: Nicotinic Acetylcholine Receptors and Microglia as Therapeutic and Imaging Targets in Alzheimer’s Disease. Molecules. 27(9):2780, 2022 (doi: 10.3390/molecules27092780).
  3. Tada AM, Hamezah HS, Arrozi AP, Abu Bakar ZH, Yanagisawa D, Tooyama I: Pharmaceutical Pptential of casein-derived tripeptide Met-Lys-Pro: Improvement in cognitive iImpairments and suppression of inflammation in APP/PS1 mice. J Alzheiemr Dis 89(3):835-848, 2022 (doi: 10.3233/JAD-220192).
  4. Uchino A, Irie Y, Tsukano C, Kawase T, Hirose K, Kageyama Y, Tooyama I, Yanagita RC, Irie K: Synthesis and Characterization of Propeller- and Parallel-Type Full-Length Amyloid β40 Trimer Models. ACS Chem Neurosci. 13(16):2517-2528, 2022 (doi: 10.1021/acschemneuro.2c00363).
  5. Shimizu S, Tojima I, Nakamura K, Kouzaki H, Kanesaka T, Ogawa N, Hashizume Y, Akatsu H, Hori A, Tooyama I, Shimizu T: A Histochemical Analysis of Neurofibrillary Tangles in Olfactory Epithelium, a Study Based on an Autopsy Case of Juvenile Alzheimer’s Disease. Acta Histochem Cytochem. 55(3):93-98, 2022. doi: 10.1267/ahc.22-00048.
  6. Pahrudin Arrozi A, Shukri SNS, Mohd Murshid N, Ahmad Shahzalli AB, Wan Ngah WZ, Ahmad Damanhuri H, Makpol S.: Alpha- and Gamma-Tocopherol Modulates the Amyloidogenic Pathway of Amyloid Precursor Protein in an in vitro Model of Alzheimer’s Disease: A Transcriptional Study. Frontiers in Cellular Neuroscience. 16:846459, 2022 (DOI: 10.3389/fncel.2022.846459).
  7. Chikugo A, Irie Y, Tsukano C, Uchino A, Maki T, Kume T, Kawase T, Hirose K, Kageyama Y, Tooyama I, Irie K: Optimization of the linker length in the dimer model of E22P-Ab40 tethered at position 38. ACS Chem Neurosci. 13(19):2913-2923 2022 (doi: 10.1021/acschemneuro.2c00436).
  8. Tsubaki H, Kageyama Y, Azu Baker ZH, Mukaisho K, Tooyama: Immunohistochemical Analysis of Mitochondrial Ferritin in the Midbrain of Patients with Parkinson’s Disease. Acta Histochem Cytochem (in press).
  9. Abu Bakar ZH, Bellier JP, Wan Ngah WZ, Yanagisawa D, Mukaisho K, Tooyama I: Optimization of 3D Immunofluorescence Analysis and Visualization Using IMARIS and MeshLab. Cells. 12: 218, 2023

2022

  1. Tsubaki H, Mendsaikhan A, Buyandelger U, Tooyama I, Walker DG. Localization of thioredoxin-interacting protein in aging and Alzheimer’s disease brains. NeuroSci. 3:166-185, 2022.
  2. Takata K, Kimura H, Yanagisawa D, Harada K, Nishimura K, Kitamura Y, Shimohama S, Tooyama I: Nicotinic Acetylcholine Receptors and Microglia as Therapeutic and Imaging Targets in Alzheimer’s Disease. Molecules. 27(9):2780, 2022 (doi: 10.3390/molecules27092780).
  3. Tada AM, Hamezah HS, Arrozi AP, Abu Bakar ZH, Yanagisawa D, Tooyama I: Pharmaceutical Pptential of casein-derived tripeptide Met-Lys-Pro: Improvement in cognitive iImpairments and suppression of inflammation in APP/PS1 mice. J Alzheiemr Dis 89(3):835-848, 2022 (doi: 10.3233/JAD-220192).
  4. Uchino A, Irie Y, Tsukano C, Kawase T, Hirose K, Kageyama Y, Tooyama I, Yanagita RC, Irie K: Synthesis and Characterization of Propeller- and Parallel-Type Full-Length Amyloid β40 Trimer Models. ACS Chem Neurosci. 13(16):2517-2528, 2022 (doi: 10.1021/acschemneuro.2c00363).
  5. Shimizu S, Tojima I, Nakamura K, Kouzaki H, Kanesaka T, Ogawa N, Hashizume Y, Akatsu H, Hori A, Tooyama I, Shimizu T: A Histochemical Analysis of Neurofibrillary Tangles in Olfactory Epithelium, a Study Based on an Autopsy Case of Juvenile Alzheimer’s Disease. Acta Histochem Cytochem. 55(3):93-98, 2022. doi: 10.1267/ahc.22-00048.
  6. Pahrudin Arrozi A, Shukri SNS, Mohd Murshid N, Ahmad Shahzalli AB, Wan Ngah WZ, Ahmad Damanhuri H, Makpol S.: Alpha- and Gamma-Tocopherol Modulates the Amyloidogenic Pathway of Amyloid Precursor Protein in an in vitro Model of Alzheimer’s Disease: A Transcriptional Study. Frontiers in Cellular Neuroscience. 16:846459, 2022 (DOI: 10.3389/fncel.2022.846459).
  7. Chikugo A, Irie Y, Tsukano C, Uchino A, Maki T, Kume T, Kawase T, Hirose K, Kageyama Y, Tooyama I, Irie K: Optimization of the linker length in the dimer model of E22P-Ab40 tethered at position 38. ACS Chem Neurosci. 13(19):2913-2923 2022 (doi: 10.1021/acschemneuro.2c00436).
  8. Tsubaki H, Kageyama Y, Azu Baker ZH, Mukaisho K, Tooyama: Immunohistochemical Analysis of Mitochondrial Ferritin in the Midbrain of Patients with Parkinson’s Disease. Acta Histochem Cytochem (in press).
  9. Abu Bakar ZH, Bellier JP, Wan Ngah WZ, Yanagisawa D, Mukaisho K, Tooyama I: Optimization of 3D Immunofluorescence Analysis and Visualization Using IMARIS and MeshLab. Cells. 12: 218, 2023